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Additionally, Diane 35 may be prescribed off-label to treat conditions such as hirsutism and polycystic ovary syndrome (PCOS), further highlighting its versatility in womens health

While acute iron exposure produced minimal biochemical changes and did not sensitize cells to oxidative or ferroptotic challenges, chronic iron exposure induced ferritin upregulation, mitochondrial superoxide accumulation, suppression of GPX4 expression, elevated lipid peroxidation and loss of cellular glutathione (GSH)

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Genetic strategies offer promising avenues for long-term resilience