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In recent studies, quercetin appears to reduce the expression of the thyroid-stimulating hormone receptor, thyroid peroxidase (TPO) and thyroglobulin (Tg) genes

PMID: 26483209

This is his third dislocation in the previous 3 years

The bifunctional complex according to claim 1, wherein the molecule comprises a ring structure selected from the group consisting of a pyrazolopyrrole, a pyrazolotetrahydrofuran, a pyrazolotetrahydropyran, a pyrazolofuran, a pyrazolothiophene, a pyrazolopyrazole, a pyrazoloimidazole, a pyrazolofurazan, a pyrazolooxazole, a pyrazoloisoxazole, a pyrazolothiazole, a pyrazoloisothiazole, a pyrazolo1,2,3-triazole, a pyrazolopyridine, a pyrazolopyridazine, a pyrazolopyrimidine, a pyrazolopyrazine, a pyrazolopiperidine, a pyrazolopiperazine, a pyrazolomorpholine, a pyrazolothiomorpholine, a pyrazoloindole, an pyrazoloisoindole, a pyrazoloindazole, a pyrazoloindolizine, a pyrazoloquinoline, a pyrazoloisoquinoline, a pyrazoloquinazoline, a pyrazolopteridine, a pyrazoloquinolizine, a pyrazolocarbazole, a pyrazolophenazine, a pyrazolophenothiazine, a pyrazolophenanthridine, a pyrazolochroman a pyrazolooxolane, a pyrazolodioxine, a pyrazoloazetidine, and a pyrazoloazepine, which ring structure may optionally be substituted by one or more substituents

PMCID: PMC9370773

Figure 2 Several recent studies have demonstrated that LPS, not only triggers innate immune responses but also induces oxidative damage and apoptosis (4549)