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A recent phase II clinical trial in Parkinsons disease, which assessed DFP in 372 newly diagnosed, untreated PD patients over 36 weeks, revealed that DFP not only failed to improve disease symptoms but was associated with a worsening of motor and non-motor symptoms compared to placebo (Devos et al., 2022)

Ferroptosis inhibitor liproxstatin-1 alleviates metabolic dysfunction-associated fatty liver disease in mice: potential involvement of PANoptosis

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Exposure to Mitomycin C (MMC) has been shown to increase ROS production in RA-FLS and disrupt m, increasing the release of mitochondrial cytochrome c and the ratio of Bax/Bcl-2 and inducing apoptosis in RA-FLS (130)