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10.1038/s41598-021-86962-0 149 KwonT.-H.ChaoD

Detailed descriptions of each step of this analysis are provided below

A meta-analysis concluded that inositol supplementation was associated with improved clinical pregnancy rates in women undergoing ovulation induction and ART

Because experimental drugs targeting acid ceramidase are already in development for other clinical applications, these findings provide an immediate framework for developing therapeutics to extend human healthspan

2014;11:e1001680

Upon stimulation, Nrf2 is released, translocates to the nucleus, and promotes the expression of antioxidant genes, including heme oxygenase 1 ( HMOX1 ), NAD(P)H quinone dehydrogenase 1 ( NQO1 ), superoxide dismutase ( SOD ), and catalase ( CAT ) (Kansanen et al., 2013