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Description

Both TMTpro and LFQ data were normalized on total peptide abundance

Cyclic GMP-AMP containing mixed phosphodiester linkages is an endogenous high-affinity ligand for STING

Cell death pathways drive necroinflammation during acute kidney injury

Foods (Basel Switzerland) 13, 23472347

In conclusion, our findings revealed the involvement of REST, a hypoxia regulatory factor, in AKI-to-CKD transition and identified the ferroptosis-inducing effect of REST, which may serve as a promising therapeutic target for ameliorating AKI and its progression to CKD