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Proof-of-concept trial with the neurosteroid pregnenolone targeting cognitive and negative symptoms in schizophrenia

pointed that SIRT1 activation may mediate the upregulation of GPX4 levels by Nrf2-HO-1 axis in the alleviation of neuronal injury

106 As confirmed by increased reduced glutathione/oxidized glutathione (GSH/GSSG) ratios, those with opioid dependency have aberrant oxidation-reduction activity

Bacterial biofilms may feed colon cancer

As a result, the model benefits from both the representational power of topological substructures and the consistency of optimized molecular inputs, allowing tree-based classifiers to more effectively learn odor-relevant motifs and distinguish subtle structural differences among fragrance compounds

doi: 10.1016/j.pep.2008.11.006 489 ZhuT.SunH.WangM.LiY