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One of them, (R)-PFI-2, inhibits the methyltransferase activity of Set7/9 at nanomolar concentrations and does not exhibit toxicity at an effective concentration in human cells 179 , 180

10.1007/s11427-024-2755-9 162 LiY.LiY.SuQ.WuY.ZhangR.LiY.et al (2022c)

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Machine-learning algorithms trained on large datasets of metalpeptide spectra can predict coordination geometry before physical measurement