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There is a lag time to reach the desired plasma concentrations at steady-state, and there will be a lag time for plasma concentrations to change in response to a dose change

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One way in which nutrition can help is by helping to reduce inflammation

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A recent study engineered a nanopyroptosis amplifier that contained lonidamine (LND) and black phosphorus nanosheets (BP) for the treatment of glioblastoma (GBM), and BP was used to block mitophagy flux and amplify LND-induced pyroptosis [94]