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102 It has also been found that nanotechnology-based formulations of antioxidant biomolecules could improve bioavailability, solubility, and stability, as well as activity

Evidence indicates it may modulate melanin synthesis pathways, though efficacy is dependent on formulation stability and skin penetration

Mol Pharmacol 2001

Targeting ferroptosis against ischemia/reperfusion cardiac injury

For example, phase I clinical trials of artesunate and ascorbic acid have been conducted (NCT02353026 and NCT01049880, respectively)

Funding This work was supported by Brookhaven National Laboratorys Program Development and by the U.S