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APAP administration worsened the hepatic oxidative stress condition, as indicated by the higher accumulation of oxidized derivatives in APAP-treated HFD fed mice compared to CD fed ones (Fig

We did not observe a non-linear relationship between PRESS GSH levels and age in this brain region in males ( P nonlinear = 0.208) or females ( P nonlinear = 0.144)

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These small molecules bind to mRNA and prevent it from being translated into a protein in the cell ribosome, thus abrogating the downstream effects of that proteins signaling (Chan 2006