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Cibinetide (ARA-290): A More Preventative, Balanced Anti-Inflammatory Approach In contrast, cibinetide (ARA-290), when given systemically (typically via subcutaneous injection), circulates and reduces inflammation more directly through selective activation of the innate repair receptor (IRR) a heterocomplex (EPOR/-common receptor or CD131) that is upregulated primarily on cells in response to tissue injury, hypoxia, metabolic stress, or inflammation

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Funding: This trial is funded by the Alzheimers Association (US), National Health and Medical Research Council (NHMRC) of Australia, and by grants from the Yulgilbar Alzheimers Research Program and Besen Family Foundation

Involvement of the thioredoxin system in multiple diseases: A focus on mechanisms of action in autophagy and ferroptosis (Review)

Cognitive function and blood methylmercury in adults living near a deserted chloralkali factory

Soriano-Mas C, editor