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Antioxidant Defense and the Aging Scalp Oxidative stress the accumulation of reactive oxygen species (ROS) in excess of the body's antioxidant defenses accelerates virtually every aspect of biological aging, including hair follicle aging

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Secondly, accurately detecting nROS currently poses significant challenges owing to the difficulties associated with fluorescent probes crossing the nuclear membrane and avoiding DNA damage response (DDR) pathways

Moreover, the increase in UV radiation on earth due to stratospheric depletion remains a major environmental threat to the human organism, increasing its risk of damage due to oxidative stress 6