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10.1111/bph.12833 73 Haberstock-DebicH.KimK.-A.YuY

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Recent studies have found that entacapone reverses ferroptosis and alleviates AKI by inhibiting lipid peroxidation and iron accumulation, with its mechanism involving the regulation of SLC7A11 to enhance antioxidant capacity ( Despite substantial progress in delineating ferroptosis-related mechanisms and potential therapeutics in I/R-induced AKI, critical knowledge gaps and translational bottlenecks persist that limit the clinical utility of these findings and hinder a holistic understanding of disease pathogenesis

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Qin Y, Wang JR, Wang Y, Iyer P, Cote GJ, Busaidy NL, Dadu R, Zafereo ME , Williams MD, Ferrarotto R, Gunn GB, Wei P, Patel K, Hofmann MC, Cabanillas ME

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