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The reported DUB-binding peptides present a potentially attractive strategy to enable DUB-target proximity by utilizing the ADs and thereby enhance selectivity while avoiding off-target effects caused by targeting via the catalytic domains

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Risk of bias The assessment of the risk of bias showed that 19 studies (61.2%) had a low risk of bias, and 6 studies (19.4%) had an unclear risk of bias

Certain health supplements can help regulate immune activity, these are commonly called immunomodulators.

We also discuss navigating hurdles such as regulatory inconsistencies, safety concerns, herbdrug interactions, and the need for standardization