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doi: 10.1096/fj.04-2377fje 115 LiCChenHDingFZhangYLuoAWangMet al

10.1016/j.ygeno.2014.01.002 72 YangL.LiG.ChaiZ.GongQ.GuoJ

A large number of clinical samples and animal experiments show that GPX4 levels are significantly decreased in degenerative cartilage tissue, and the degree of its downregulation correlates with the severity of articular cartilage destruction, matrix degradation, and inflammation (Miao et al., 2022

Our prediction-based approach reveals a previously undescribed folded domain, which we could confirm experimentally

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