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doi: 10.1016/j.molcel.2021.09.010 337 SunL.WuJ.DuF.ChenX.ChenZ

2017;12(4):e0174443

Furthermore, esculin treatment significantly downregulated IL-1 expression, indicating its potential to modulate macrophage-driven inflammatory responses, likely through inhibition of critical signaling pathways such as NF-B

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As we stated in section VI.C.2.b.(3) of this proposed rule, we did not include exclusions for medical contraindications because the PFAs we met with told us that a measure capturing raw vaccination rate, irrespective of any medical contraindications, would be most helpful in patient and family/caregiver decision-making

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