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Similarly to XO, XDH also transfers hypoxanthine to xanthine and xanthine to uric acid, however, XDH uses NAD + as the substrate

CIPN can progress from acute to chronic, may deteriorate even after treatment cessation (a phenomenon known as coasting) or only partially attenuate

is a nonradioactive method for determining vitamin B12 absorption and bioavailability

In addition, thermally responsive hydrogels have been designed to release VEGF in response to body temperature stimulation to promote the healing of diabetic wounds (Shi et al., 2022)