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*Correspondence: Ye Qiu, [email protected] Weng, [email protected] These authors have contributed equally to this work and share first authorship Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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And then the other thing, of course, is just that when you do generate the oxidants if you can neutralize them right then and there before they slip away and start slipping into the nucleus where they are going to change gene expression or slipping way out into the edges of the cell where they are going to shut glucose metabolism down, then, you know, then youre not going to have those adaptive responses of shutting down the incoming energy and turning off energy metabolism

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