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Reportes de casos en humanos: limitados, heterogneos en metodologa

We detected minimal activity of ABHD11 against succinyl esters, but this analysis was hampered by the spontaneous hydrolysis of the succinyl compounds

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This link between TNF- and ROS adds another dimension of complexity to the TNF signalling network, as ROS act on numerous proteins required for the regulation of cellular homeostasis, including proteins that mediate cell proliferation, survival, death, differentiation, DNA repair and metabolism 30

2010;6:e1000852

Monitoring symptoms, managing lifestyle triggers, and seeking timely medical advice are key