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For example, while moderate ROS often drive tumorigenic processes by enhancing prosurvival signaling, high ROS levels can inhibit these same pathways, such as PI3K/AKT, leading to growth arrest or cell death

Comparison of demographic characteristics and clinical variables between two study groups were assessed using 2 Yatess continuity correction or Fishers exact tests for categorical variables and Mann-Whitney u test for non-normally distributed continual variables

Correlation analysis of the p53 expression and enzymatic activities upon variations in cellular thiamine/ThDP levels indicates that p21 knockdown substitutes positive correlation of the p53 expression with the activity of 2-oxoglutarate dehydrogenase complex (OGDHC) for that with the activity of glutamate dehydrogenase (GDH)

Depression (PHQ-9) scores only showed a negative correlation with GSH ( r = 0.16, P 0.05)

J.St-JacquesB.ShenL.MohlerJ.McMahonJ

doi: 10.1007/s12325-023-02776-8 182 ChoiKYKimHIRheeCKet al