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Minihane AM, Vinoy S, Russell WR, Baka A, Roche HM, Tuohy KM, Teeling JL, Blaak EE, Fenech M, Vauzour D, McArdle HJ, Kremer BH, Sterkman L, Vafeiadou K, Benedetti MM, Williams CM, Calder PC

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2-[4-(2-Hydroxyethyl)piperazin-1-yl]ethane-1-sulfonic acid (HEPES) was purchased from Shanghai Mackin Biochemical Co., Ltd

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C.Induction of oxidative stress response by the mycotoxin patulin in mammalian cellsToxicol

In osteoarthritis (OA), the inhibition of the Nrf2 pathway leads to decreased activity levels of SOD and CAT, impairing the antioxidant defense systems ability to eliminate reactive ROS and increasing the risk of ferroptosis effectively