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The search strategy employed a combination of the following keywords and MeSH terms: Parkinsons disease, ferroptosis,lipid peroxidation, alpha-synuclein, microglia, astrocytes, therapeutics, and neuroprotection. The inclusion criteria focused on original research articles, reviews, and clinical trials published in English that elucidated molecular mechanisms, pathological features, or therapeutic strategies related to ferroptosis in PD

331,332 As a bridge of intercellular communication, classical exosomes have a monolayer structure, which can encapsulate bioactive substances, such as proteins, lipids, DNA, and RNA, in the core and deliver them to effector cells to play specific biological functions (Fig

19 , e45595 (2018)

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