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doi: 10.1089/ars.2007.1716 9 DrydenM

Science 276:16991702, PMID: 9180080 Takaki J, Fujimori K, Miura M, Suzuki T, Sekino Y, Sato K (2012) l-glutamate released from activated microglia downregulates astrocytic l-glutamate transporter expression in neuroinflammation: the collusion hypothesis for increased extracellular l-glutamate concentration in neuroinflammation

Other methods, like intravenous injection, can be difficult and costly

Front Med Lausanne

Guerra-De-Blas PDC, Bobadilla-Del-Valle M, Sada-Ovalle I, Estrada-Garca I, Torres-Gonzlez P, Lpez-Saavedra A, Guzmn-Beltrn S, Ponce-de-Len A, Sifuentes-Osornio J

Besides that, purine and pyrimidine synthesis use also glutamine-derived aspartate, whose supplementation can rescue cell cycle arrest caused by glutamine deprivation [44]