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More concerning are findings from systematic reviews and meta-analyses indicating dose-dependent hepatotoxicity and an increased risk of clinically significant liver enzyme elevations, especially when CBD is taken with drugs like valproate that share metabolic pathways

and traumatic brain injury (Ismail et al., 2020)

Nature 140 , 281-281 (1937)

A., et al., Proc.Nat'l.Acad.Sci.USA, 85:8998-9002 (1988)

B., Richardson, W

Following spirometry, EBC from children aged 712 years, from the Respiratory Health Outcomes in Neonates study, were analysed using Time-of-Flight Mass Spectrometry