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Plants 11 , 2524 (2022)

We examine dysfunction across various conditions and analyze emerging therapeutic approaches targeting thermogenic activation and cellular senescence pathways, providing an integrated framework for understanding metabolic disease pathogenesis and identifying novel intervention strategies

Additionally we found patients with intermediate PDFF (5-10%) have the best survival outcomes, suggesting PDFF as a valuable survival predictor

B12 deficiency can lead to neurological symptoms including numbness, tingling in the extremities, difficulty walking, and memory problems

Mechanism of action of isothiocyanates: the induction of ARE-regulated genes is associated with activation of ERK and JNK and the phosphorylation and nuclear translocation of Nrf2

More importantly, exercise-based therapy to reduce body weight for the treatment of KOA is consistently recommended in treatment guidelines [9]