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It covers the fundamental principles of OoC, explains how these systems are designed and fabricated, and highlights the technological advancements that underpin their development

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3.10 Traumatic brain injury and stroke Traumatic brain injury (TBI) and ischemic stroke are common acute central nervous system injuries that share a characteristic cascade: following the initial mechanical or perfusion insult, mitochondrial dysfunction ensues, leading to excessive reactive oxygen species (ROS) production, calcium overload, and neuronal apoptosis

On follow up after one year, he developed peak dose dyskinesia & treatment was modified, to which he responded