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Thus, rapid administration of NAC after ingestion provides the most benefit, ideally within 8 hours

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Additionally, older adults are particularly vulnerable to drug-induced hyperkalemia, attributed to the active transport of urinary potassium within the distal renal tubules and collecting ducts, a process that is closely linked to sodium reabsorption mediated by the aldosterone-regulated Na-K ATPase transporter

Caboni, P

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Cell pellets were resuspended in Lysis Buffer (25 mM HEPES/NaOH pH 7.5, 500 mM NaCl, 5% glycerol, 1 mM DTT) supplemented with 0.02 mg/mL DNase I and lyzed using a continuous flow cell disrupter (Constant Systems)