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50 Furthermore, inflammation may significantly affect MSC metabolic activity, differentiation, and viability

In contrast to FSP1 function in extramitochondrial membranes, DHODH has been identified as a mitochondrial suppressor of ferroptosis through reducing CoQ10 to block lipid peroxidation in mitochondria

aad.org Draelos ZD, et al

These protective effects involve activation of cell survival pathways and may include antioxidant mechanisms, though the precise molecular pathways mediating cytoprotection require further elucidation