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We show that inhibition of ATP synthesis caused a marked intracellular accumulation of pyroglutamate, reflecting decreased GSH synthesis

Importantly, this dual engineering approach results in on-target and IgG subclass specific effector molecule engagement, giving rise to a toolbox that can guide design of IgG antibodies with tailored mode-of-action towards a specific target and indication

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Rosa26 mTmG mice 24 h before animals were subjected to a single dose of IR (Fig 6A)

Stability & Storage Storage/Stability Aliquot and store at -70C

PubMed (pubmed.ncbi.nlm.nih.gov): For offering access to a vast repository of peer-reviewed studies on GPx isoforms, their mechanisms, and clinical significance