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CHE exerts antitumor activity by possessing a solid affinity for inhibiting the telomerase activity by substrate sequestration through G-quadruplex stabilization, which leads to fast proliferation of cells, thus promoting tumor cell death (Noureini et al., 2017)

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Alcoholism: Clinical and Experimental Research 31 , 10531060, doi: 10.1111/j.1530-0277.2007.00393.x (2007)

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doi: 10.1016/0169-328X(94)00273-H 34 Ebrahimi-FakhariD.WahlsterL.McLeanP

KruskalWallis, followed by Dunns test, was applied for statistical analysis of Johnsens score between groups