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1A), alone and in combination with Telaglenastat (CB-839), a selective glutaminase inhibitor of both splice variants of glutaminase (KGA and GAC) with good oral bioavailability [63, 64], currently in phase II clinical trials (NCT04265534)

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The IL-6/IL-6R signal promotes the formation of an immune-inflammatory microenvironment by inducing KP activation in pulmonary vascular cells (Cai et al., 2022)

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In HCECs applied with desiccating stress, the CEC ferroptosis was triggered by the aggregation of autophagy impairment-derived sequestosome 1 (SQSTM1), the overexpression of which fostered ferroptotic changes and substantially elevated ACSL4 (124)

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In addition, preliminary evidence suggests that vitamin C can accumulate in neutrophils to an extent

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[DOI] [PubMed] [Google Scholar] Monks TJ, Ghersi-Egea JF, Philbert M, Cooper AJ, Lock EA

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