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10.1016/j.trecan.2021.10.004 39 CramerT.YamanishiY.ClausenB

A screening of 939 miRNAs highlighted, with respect to the above profiling studies, the downregulation of miR-195 and miR-497 and the upregulation of miR-424 in CRC tissues with respect to non-cancerous mucosa (90)

J.GriessenauerC

Gel-shift analysis revealed reduced LXR binding activity in the I148M oe M1 macrophage, leading to the downregulation of ABCA1 (-36.7%) and ABCG1 (-32%)

In vitro prophylactic injection of IL-22 can significantly reduce the expression of pro-inflammatory factors IL-6, IL-1, TNF-, and the liver necrosis area and increase the expression of hepatocyte proliferation marker Ki-67, suggesting that IL-22 through promoting hepatocyte proliferation mediates hepatoprotective functions and has the therapeutic potential in AILI [174]