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Peroxisome proliferator-activated receptor gamma coactivator-1 alpha (PGC-1) governs this process by activating multiple transcription factors, including nuclear respiratory factors 1 and 2 (NRF-1 and NRF-2) and mitochondrial transcription factor A (TFAM) (46)

Cells subjected to Cys 2 starvation or BSO and erastin coincubation did not alter MitoTracker fluorescence intensity (Fig

Therefore, all body systems can be affected by the state of the glutathione system, especially the immune system, the nervous system, the gastrointestinal system, and the lungs

Norppa et al., 1985

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Our teams observations show that this mechanism directly impacts the energy balance within cells, encouraging them to burn fat for fuel rather than store it