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Data from clinical studies have also shown that renal impairment in patients with overweight or obesity does not impact the pharmacokinetics of tirzepatide [see Use in Specific Populations (8.6)]

Specifically, one commenter suggested that CMS consider unpackaging their product, a contrast agent, and believed CMS's reasoning in the CY 2026 OPPS/ASC proposed rule for unpackaging and paying separately for diagnostic radiopharmaceuticals applies equally or even more to their product, since the cost of their product is over 500 times greater than the amount reported for the policy packaged drugs offset associated with the Level II Urology APC

CPT codes commonly billed with Z02.2 The ICD-10 diagnosis code Z02.2 pairs with an E/M procedure code for the examination itself

Patients who have a lot of inflammation (i.e., a lot of the intestine is involved)

To the extent the data shows that there would be more than a limited impact on the relative weights initially, which we do not believe will be the case, we intend to provide an opportunity for the public to review the data we collect prior to implementation

Free T3 drops while TSH stays in range