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These data support the possibility of local-delivery applications (e.g., topical, inhalation, or GI mucosal targeting) where the short-lived reactive parent compound can act at the site of infection without requiring prolonged systemic exposure (Oluwabusola et al., 2022

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Comp Biochem Physiol A Mol Integr Physiol

The small sample size (n=25 in each group), complicated with a high dropout rate from the treatment group (9 out of 25) in this trial exhorts a cautious interpretation of the results

The most preferred are sertraline, and paroxetine (generally not used in pregnancy because of teratogenicity in first trimester) because these are the best studied, and they have low infant exposure and fewer adverse effects

Molybdenum deficiency is a rare condition, with symptoms associated with genetic defects in enzymes involved in molybdopterin synthesis