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The hypothesis has expanded to include vascular dysfunction, oxidative stress, microglial activation, and impaired proteolysis (Roda et al., 2022)

Hemoglobin autooxidation/oxidation mechanisms and methemoglobin prevention or reduction processes in the bloodstream

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Additionally, the inoculation of Pediococcus was 1 10 6 log 10 CFU/g FW, 5 10 5 log 10 CFU/g FW, and 5 10 5 log 10 CFU/g FW in these groups, respectively

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[7] [9] Patients with hemochromatosis or other iron overload disorders should not receive large doses of ascorbic acid, as it can enhance iron absorption and exacerbate tissue deposition