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GSH plays a major role in resistance to conventional chemotherapy, while promoting tumor recurrence

Historically, peroxiredoxins have been divided into three classes: typical 2-Cys PRXs, atypical 2-Cys PRXs, and 1-Cys PRXs

However, it also inhibits NOX-2, -3 and -4 and XO to some extent

Exposure to cadmium also potentially reduces cerebral blood flow (158) [particularly cortical blood flow (159)], as cadmium has a disruptive effect on angiogenesis (160)

Elevated heme levels are a hallmark of multiple cancers, reflecting an adaptive rewiring of metabolism rather than a passive accumulation

The intervention group had no change in GSH concentrations in the frontal region