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Description

In addition, how the supplementation dose of small molecular antioxidants affects their intracellular levels and whether radical scavenging activity at the site of action is feasible are unknown

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doi: 10.1186/s13293-024-00630-2 96 QinYWangYZhaoHYangZKangY

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An RCT in patients receiving cisplatin chemotherapy found that NAC (1,200 mg/day) significantly reduced nephrotoxicity and ototoxicity without reducing antitumor efficacy (Riga et al., Am J Clin Oncol, 2013) [77]

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