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View Abstract MRI findings of juvenile psoriatic arthritis

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Upon release, celecoxib inhibited COX-2, reduced the production of PGs, MMPs, and cytokines, specifically in areas with high MMP13 activity

However, at a pH below 6, secondary nucleation is favoured than fibril growth thus shifting the kinetics of fibrillation towards formation of toxic protofibrils (Frey et al., 2024)