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The safety window is unusually wide

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[3334] demonstrated that the presence of long chain FA in the perfusion medium during Langendorff perfusion of db/db hearts increased O 2 consumption and impaired the ATP/O ratio, indicating FA-induced mitochondrial uncoupling

Bioenergetics and translational metabolism: implications for genetics, physiology and precision medicine

1 Introduction In the past decades, the global morbidity of cancer has increased, and cancers have become the leading cause of mortality worldwide

The application of transcriptomics, animal models, and spatial analysis techniques has introduced novel strategies for elucidating their mechanisms of action