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11 This may help explain the multi-systemic nature of symptoms, which can include sweating abnormalities, bowel and bladder disturbances, dry eyes, dry mouth, gastrointestinal dysmotility, skin changes (eg, discoloration, loss of hair, shiny skin), sexual dysfunction, orthostatic hypotension, and palpitations

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doi: 10.1096/fj.202400088R 41 WangYDuanHZhangJWangQPengTYeXet al

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Doctors often start with daily or weekly doses for a few weeks

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