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Side effects Common: Nausea (40% of users, usually mild) Flushing (21%) Headache (11%) Injection site reactions Tips for managing nausea: Taking an anti-nausea medication beforehand can help

Administration of 300 mg/kg of APAP led to 100% mortality within 6 h, but 1,000 mg/kg of natsumikan extract and silymarin prolonged survival rates to 33.3% and 50.0%, respectively

PMCID: PMC7569385.

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10.1001/jama.2014.3192 2

JCI Insight 4 Liu X, Xie X, Ren Y, Shao Z, Zhang N, Li L, Ding X, Zhang L (2021) The role of necroptosis in disease and treatment