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CYP2E1 induction increases with repeated high-dose alcohol exposure and contributes significantly to ethanol clearance in individuals with alcohol use disorder (AUD)

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We next investigated the NHR-49::YFP 295422 truncation to better understand how impaired ligand binding impacts its subcellular dynamics and transcriptional activity during fasting and refeeding

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doi: 10.3390/biom13010082 241 MohamedMMAEl-ShimyIAHadiMA

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Direct addition of a GSH analog (GSH-OEt) able to enter cells due to its hydrophobic ester groups also increased cell death in TNF- -treated cell cultures (Figure 4B), thus imitating the ability of hGH to sensitise control U937 cells to TNF- -induced apoptosis

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