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Thus, the implication of ROS in Cd-dependent modulation of autophagy was investigated in cells treated with the antioxidant NAC or BSO, which inhibits glutathione synthesis and promotes pro-oxidant conditions

Vergouw, L

Amsterdam, Netherlands: NanoImpact

Consequently, the subacute stage represents a pivotal therapeutic window for interventions aimed at limiting secondary degeneration, modulating oxidative and iron-dependent (ferroptotic) injury cascades, and promoting neuroplasticity

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GSHthe most abundant antioxidant molecule in the braineither acts directly as a ROS scavenger or can be used as a substrate for glutathione S-transferase or glutathione peroxidase