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Immune regulation within the tumor microenvironment plays a critical role in tumor progression and chemotherapy resistance

J Gastrointest Surg 2006

But is it really the key to maintaining a youthful, biological age

However, some cells and tissues with high energy demands, such as the endothelial cells, -cells and neurons, do not adapt their glucose transport efficiently enough, which results in increased intracellular glucose concentrations

The intrinsic (mitochondrial) pathway is initiated by severe cellular stress, including DNA damage, ER stress, and oxidative overload

Recent studies have identified imbalances in copper homeostasis across various cancers, along with the emergence of cuproptosis, a novel copper-dependent form of cell death that is crucial for tumor suppression and therapeutic resistance