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In recent years, alternatives have been investigated to reduce or replace FBS in mammalian cell culture

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10.1021/acs.jafc.7b01707 66 QiX.SunX.ZhuL.ZhangH.WangY.LiuY.et al (2022)

After 1 h of SA treatment, increased H 2 O 2 levels and GSH-dependent redox potential values were measured, demonstrating a more oxidized redox environment in the cells

Similarly in protonated Gt heteroatoms such as N6 (0.56), O10 (0.52), N14 (0.51), N9 (0.52), O19 (0.52), N14 (0.51), O15 (0.51), O1 (0.45), O4 (0.45), and O18 (0.43) show high negative Mulliken charges

(55) further demonstrated that in models of PD and other neurodegenerative diseases, EGCG exerts neuroprotective effects via NF-B signaling inhibition by blocking IB phosphorylation and suppressing p65 nuclear translocation, thus downregulating pro-inflammatory cytokines such as TNF- and IL-1 and reducing dopaminergic neuronal loss and motor dysfunction