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Patients with PFIC3 might not show symptoms until 23 years old, unlike those with PFIC1 and PFIC2 [1, 2, 42, 44]

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Indeed, in patients with subclinical hypothyroidism or iodine deficiency, soy isoflavonoids ingestion may lead to clinically relevant effects [161]

In this work, the water soluble HA and PVA polymers used as structural material for the DDMNs are non-crosslinked, therefore, can be soluble in tissue

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