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1 3 However, research using knockout mice unable to synthesize vitamin C endogenously showed normal carnitine values (comparable to their vitamin C synthesizing counterparts), although they were vitamin C deficient

Since LC concentration in skeletal muscles is higher than that of blood plasma, active uptake of carnitine must take place [23]

Belcaro G, Cornelli U, Dugall M, Hosoi M, Cotellese R, Feragalli B

Upon careful estimation, we determined that assigning 135 patients to both the study and control groups would yield more than 80% power to detect between-group differences

Is this a known problem

ScienceDirect Salehpour S, Nazari L, Hoseini S, Moghaddam PB, Gachkar L