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PLoS One 15, e0240789 (2020), Abstract Full Text 4-Phenylbutyrate ameliorates apoptotic neural cell death in Down syndrome by reducing protein aggregates: K

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Indeed, PM2.5 has been demonstrated to inflict damage upon a multitude of bodily systems through the induction of oxidative stress, inflammation, and regulated cell death (including apoptosis, necroptosis, and pyroptosis) [65, 66]

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MtDNA is vulnerable to direct attack by ROS, leading to oxidative damage and mutations that disrupt mitochondrial function

At our practice, IV therapyparticularly corticosteroid infusions such as methylprednisoloneis routinely administered to reduce inflammation, shorten symptom duration, and accelerate recovery