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The catalytic parameters and substrate specificity of GPx6 are not known as the protein has not been purified yet [1, 8]

These inhibitors not only prevent necroptotic cell death but also play a crucial role in suppressing NLRP3 inflammasome activation, thereby reducing neuroinflammation and neuronal damage in models of glutamate-induced excitotoxicity (113)

Several pediatric studies have demonstrated that concomitant celiac disease in children with AIH is associated with a milder liver disease course, better response to treatment, and higher chances of immunosuppression withdrawal [38, 40, 41]

Contribution of glycation and oxidative stress to thyroid gland pathology-a pilot study

113,114 Wnt/-catenin pathway in other cardiovascular diseases LRP5 regulates body fat distribution through the canonical Wnt signalling pathway and affects the occurrence of cardiometabolic disorders, which is consistent with the increased prevalence of cardiovascular disease in subjects with abdominal obesity

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